Structural and evolutionary analysis of an orangutan foamy virus.
نویسندگان
چکیده
The full-length proviral genome of a foamy virus infecting a Bornean orangutan was amplified, and its sequence was analyzed. Although the genome showed a clear resemblance to other published foamy virus genomes from apes and monkeys, phylogenetic analysis revealed that simian foamy virus SFVora was evolutionarily equidistant from foamy viruses from other hominoids and from those from Old World monkeys. This finding suggests an independent evolution within its host over a long period of time.
منابع مشابه
The phylogeography of orangutan foamy viruses supports the theory of ancient repopulation of Sumatra.
Phylogenetic analysis of foamy virus sequences obtained from Bornean and Sumatran orangutans showed a distinct clustering pattern. One subcluster was represented by both Bornean and Sumatran orangutan simian foamy viruses (SFV). Combined analysis of host mitochondrial DNA and SFV phylogeny provided evidence for the hypothesis of the repopulation of Sumatra by orangutans from Borneo.
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عنوان ژورنال:
- Journal of virology
دوره 77 15 شماره
صفحات -
تاریخ انتشار 2003